Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA9 | Q16790 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899327 | 0.98 | ALOX12 (0.57) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL11818238 | 0.98 | ALOX12 (0.57) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL3068928 | 0.82 | ALOX12 (0.65) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL3072835 | 0.82 | CA12 (0.59) | ALOX12ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL20022983 | 0.79 | ALDH1A1 (0.53) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL9153056 | 0.79 | GAA (0.50) | ALOX12ALDH1A1HPGDGAAMAPT | |
| SCHEMBL3068669 | 0.78 | CA12 (0.55) | ALOX12ALDH1A1HPGDMEN1POLB | |
| SCHEMBL2240540 | 0.78 | CA12 (0.55) | ALDH1A1GAAKMT2ACA12CA1 | |
| SCHEMBL24487049 | 0.78 | CA1 (0.46) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL3068672 | 0.77 | ALDH1A1 (0.55) | ALDH1A1POLBKMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092579-B2 | Gold(I) complexes with anticancer properties and methods of use thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2018-10-09 | — | — | US | disclosed |
| US-20170232012-A1 | GOLD(I) COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-08-17 | — | — | US | disclosed |
| US-20170197997-A1 | GOLD(I) COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-07-13 | — | — | US | disclosed |
| US-9573967-B2 | N-heterocyclic carbene gold complexes with anticancer properties and methods of use thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2017-02-21 | — | — | US | disclosed |
| US-20160326187-A1 | N-HETEROCYCLIC CARBENE GOLD COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2016-11-10 | — | — | US | disclosed |
| US-9278905-B2 | Production method for compound comprising amino group and/or hydroxyl group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-03-08 | — | — | US | disclosed |
| US-9278905-B2 | Production method for compound comprising amino group and/or hydroxyl group | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2016-03-08 | — | — | US | disclosed |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| EP-2821389-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | Kyushu University, National University Corporation (JP) | 2015-01-07 | — | — | EP | disclosed |
| EP-0873375-A1 | USE OF A COMBINATION OF SILICONE COMPOUNDS AS A COUPLING AGENT IN SILICA-LOADED ELASTOMER COMPOSITIONS | RHODIA CHIMIE (FR) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997025374-A1 | USE OF A COMBINATION OF SILICONE COMPOUNDS AS A COUPLING AGENT IN SILICA-LOADED ELASTOMER COMPOSITIONS | RHODIA CHIMIE (FR) | 1997-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10092579-B2 | Gold(I) complexes with anticancer properties and methods of use thereof | MCL1, BAD, TP53 | ALOX12 4150/4885ALDH1A1 1409/4885HPGD 2966/4885 |
| US-20170232012-A1 | GOLD(I) COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF | MCL1, BAD, TP53 | ALOX12 4150/4885ALDH1A1 1409/4885HPGD 2966/4885 |
| US-20160326187-A1 | N-HETEROCYCLIC CARBENE GOLD COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF | MCL1, HCCS, ACIN1 | ALOX12 2085/4885ALDH1A1 1094/4885HPGD 522/4885 |
| US-20170197997-A1 | GOLD(I) COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF | MCL1, BAD, TP53 | ALOX12 4150/4885ALDH1A1 1409/4885HPGD 2966/4885 |
| US-20150105559-A1 | PRODUCTION METHOD FOR COMPOUND COMPRISING AMINO GROUP AND/OR HYDROXYL GROUP | CA7, DAO, CA4 | ALOX12 1925/4885ALDH1A1 732/4885HPGD 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.