Stearic Acid

Stearic Acid

SCHEMBL873217

CCCCCCCCCCCCCCCCCC(=O)O.NCC(=O)O.[MgH2]

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.77
PPARG P37231 7/20 0.77
PPARD Q03181 7/20 0.77
PPARA Q07869 7/20 0.77
HDAC11 Q96DB2 5/20 0.77
TSHR P16473 4/20 0.77
PTPN1 P18031 3/20 0.77
FABP4 P15090 3/20 0.77
ALDH1A1 P00352 2/20 0.77
TLR2 O60603 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
KMT2A Q03164 2/20 0.77
ALOX15 P16050 2/20 0.77
HSD17B10 Q99714 2/20 0.77
SLC22A6 Q4U2R8 1/20 0.77
SLC22A8 Q8TCC7 1/20 0.77
MEN1 O00255 1/20 0.77
ESR1 P03372 1/20 0.77
PDE4A P27815 1/20 0.77
PDE3A Q14432 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Octanoic Acid SCHEMBL1031982 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Hexacosanoic Acid SCHEMBL8585366 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Myristic Acid SCHEMBL7533929 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL31288181 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL28507105 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL28497727 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL2712826 0.98 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL29648512 0.95 GPR84 (0.77) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL5078569 0.93 GPR84 (0.74) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL9164233 0.93 GPR84 (0.81) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260021147-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISEASE UNIV MICHIGAN REGENTS (US) 2026-01-22 US disclosed
US-20250295712-A1 COMPOSITIONS AND METHODS FOR MODULATING GUT MICROBIOMES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-09-25 US disclosed
US-20240415896-A1 ANTIMICROBIAL COMPOSITIONS CORNELL UNIVERSITY 2024-12-19 US disclosed
EP-4475861-A1 COMPOSITIONS AND METHODS FOR MODULATING GUT MICROBIOMES The Regents Of The University Of Michigan (US) 2024-12-18 EP disclosed
WO-2024102831-A2 MODULATION OF THE GUT MICROBIOME FOR ENHANCEMENT OF GUT AND BRAIN HEALTH THE CLEVELAND CLINIC FOUNDATION (US) 2024-05-16 WO disclosed
WO-2024073432-A2 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISEASE THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-04-04 WO disclosed
US-11931386-B2 Compositions and methods for increasing butyrate production THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-03-19 US disclosed
US-11883444-B2 Inhibition of enteric infection through the modulation of microbiota THE UNIVERSITY OF CHICAGO (US) 2024-01-30 US disclosed
US-20230364162-A1 METHODS AND COMPOSITIONS FOR INTESTINAL INFLAMMATION THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2023-11-16 US disclosed
WO-2023154787-A1 COMPOSITIONS AND METHODS FOR MODULATING GUT MICROBIOMES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-08-17 WO disclosed
US-20090324547-A1 Probiotic Oral Health Promoting Product WIKSTROM, MAUDE (SE) 2009-12-31 US disclosed
US-20090285858-A1 PREVENTION OF ALLERGY IN CHILDREN FORSKARPATENT I SYD AB (SE) 2009-11-19 US disclosed
EP-1978979-A1 PROBIOTIC ORAL HEALTH PROMOTING PRODUCT WIKSTRÖM,, Maude (SE) 2008-10-15 EP disclosed
US-20080031897-A1 PREVENTION OF ALLERGY IN CHILDREN FORSKARPATENT I SYD AB (SE) 2008-02-07 US disclosed
US-20070207169-A1 EARLY CHILDHOOD INFECTION WITH HUMAN HERPES VIRUS TYPE 6 (HHV-6) AS A PROTECTION AGAINST THE DEVELOPMENT OF IGE SENSITIZATION, ATOPIC DISEASE AND ALLERGY IN YOUNG CHILDREN FORSKARPATENT I SYD AB (SE) 2007-09-06 US disclosed
WO-2007077210-A1 PROBIOTIC ORAL HEALTH PROMOTING PRODUCT WIKSTROEM MAUDE (SE) 2007-07-12 WO disclosed
EP-1796699-A1 EARLY CHILDHOOD INFECTION WITH HUMAN HERPES VIRUS TYPE 6 (HHV-6) AS A PROTECTION AGAINST THE DEVELOPMENT OF IGE SENSITIZATION, ATOPIC DISEASE AND ALLERGY IN YOUNG CHILDREN. Forskarpatent i Syd AB (SE) 2007-06-20 EP disclosed
EP-1789083-A1 PREVENTION OF ALLERGY IN CHILDREN Forskarpatent i Syd AB (SE) 2007-05-30 EP disclosed
WO-2006031195-A1 EARLY CHILDHOOD INFECTION WITH HUMAN HERPES VIRUS TYPE 6 (HHV-6) AS A PROTECTION AGAINST THE DEVELOPMENT OF IGE SENSITIZATION, ATOPIC DISEASE AND ALLERGY IN YOUNG CHILDREN. FORSKARPATENT I SYD AB (SE) 2006-03-23 WO disclosed
WO-2006009501-A1 PREVENTION OF ALLERGY IN CHILDREN FORSKAPATENT I SYD AB (SE) 2006-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021147-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISEASE MUC1, O60361, BPGM GPR84 1481/4885PPARG 2173/4885PPARD 1659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.