SCHEMBL8732397

SCHEMBL8732397

CCc1cc(Cc2cc(CC)c(N3C(=O)C=CC3=O)cc2C)c(C)cc1N1C(=O)C=CC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.50
HSP90AA1 P07900 4/20 0.44
ALDH1A1 P00352 4/20 0.44
CCR6 P51684 3/20 0.44
MAPT P10636 3/20 0.44
NPSR1 Q6W5P4 3/20 0.44
PKM P14618 2/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
NLRP1 Q9C000 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TLR9 Q9NR96 2/20 0.36
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
CACNA1B Q00975 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732400 0.85 HSP90AA1 (0.46) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL8732387 0.85 MGLL (0.53) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL331584 0.79 MGLL (0.50) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL8027104 0.78 MGLL (0.46) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL27850421 0.78 MGLL (0.53) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL9418756 0.74 MGLL (0.58) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL8733732 0.74 MGLL (0.44) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL28621362 0.73 MGLL (0.47) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL27558829 0.73 MGLL (0.61) MGLLHSP90AA1ALDH1A1CCR6MAPT
SCHEMBL29929064 0.71 MGLL (0.59) MGLLHSP90AA1ALDH1A1NPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2557121-A1 RESIN COMPOSITION, PREPREG AND LAMINATE Mitsubishi Gas Chemical Company, Inc. (JP) 2013-02-13 EP disclosed
US-5725948-A POLYIMIDE FROM A BISMALEIMIDE AND A DIAMINE TOMOEGAWA PAPER CO., LTD. (JP) 1998-03-10 US disclosed