SCHEMBL8733732

SCHEMBL8733732

CCCc1cc(N2C(=O)C=CC2=O)c(CCC)cc1Cc1cc(CCC)c(N2C(=O)C=CC2=O)cc1CCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 13/20 0.44
TLR9 Q9NR96 2/20 0.35
FAAH O00519 3/20 0.35
ALDH1A1 P00352 5/20 0.33
HSP90AA1 P07900 4/20 0.33
NPSR1 Q6W5P4 4/20 0.33
MAPT P10636 3/20 0.33
CCR6 P51684 3/20 0.33
HPGD P15428 3/20 0.33
HTT P42858 3/20 0.33
PKM P14618 2/20 0.33
RAB9A P51151 2/20 0.33
CACNA1B Q00975 2/20 0.33
APBA1 Q02410 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
G6PD P11413 1/20 0.33
NLRP1 Q9C000 1/20 0.33
LMNA P02545 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8727167 0.90 MGLL (0.42) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL8732387 0.84 MGLL (0.53) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL19511516 0.77 MGLL (0.51) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL331584 0.74 MGLL (0.50) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL8732397 0.74 MGLL (0.50) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL9837583 0.73 MGLL (0.50) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL3774325 0.71 MGLL (0.79) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL30302472 0.71 MGLL (0.79) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL27560932 0.71 MGLL (0.43) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL8854671 0.70 MGLL (0.47) MGLLFAAHALDH1A1HSP90AA1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5725948-A POLYIMIDE FROM A BISMALEIMIDE AND A DIAMINE TOMOEGAWA PAPER CO., LTD. (JP) 1998-03-10 US disclosed