Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 2/20 | 0.54 |
| ▸ | ULK1 | O75385 | 1/20 | 0.50 |
| ▸ | KHK | P50053 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.46 |
| ▸ | PFKFB2 | O60825 | 2/20 | 0.46 |
| ▸ | PFKFB1 | P16118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10327297 | 1.00 | SCN3A (0.55) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL17676974 | 1.00 | SCN3A (0.55) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL24609551 | 0.88 | SCN3A (0.55) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL7198731 | 0.87 | LMNA (0.61) | PKMPOLBMAPTSMN1; SMN2 | |
| SCHEMBL13388756 | 0.87 | SCN3A (0.64) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL29365790 | 0.86 | SCN3A (0.56) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL7692273 | 0.86 | SCN3A (0.56) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL13379539 | 0.84 | SCN3A (0.58) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL1750392 | 0.84 | SCN3A (0.58) | SCN3ASCN9APSMB8DHODHULK1 | |
| SCHEMBL1751199 | 0.84 | SCN3A (0.55) | SCN3ASCN9APSMB8DHODHULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024197653-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUZHOU EOC MEDICAL RESEARCH CO., LTD. (CN) | 2024-10-03 | — | — | WO | disclosed |
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |
| EP-2438989-B1 | USE OF ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO PERFUMERY CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8399684-B2 | Sulfonamide-based organocatalysts and method for their use | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2013-03-19 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100184986-A1 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | The State of Oregon acting by and through the State Board of Higher Education on behalf of Orego | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184986-A1 | SULFONAMIDE-BASED ORGANOCATALYSTS AND METHOD FOR THEIR USE | ALDH7A1, SULT1A1, SULT2A1 | SCN3A 3398/4885SCN9A 1598/4885PSMB8 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.