Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733003 | 1.00 | MAPT (0.65) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8733295 | 0.88 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8733294 | 0.88 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8729720 | 0.87 | MMP1 (0.70) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8729717 | 0.87 | MMP1 (0.70) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8727675 | 0.86 | MMP1 (0.64) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8727681 | 0.86 | MMP1 (0.64) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL8181735 | 0.79 | AKR1B1 (0.73) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL10492259 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL1315178 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |