Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.70 |
| ▸ | MMP2 | P08253 | 1/20 | 0.70 |
| ▸ | MMP13 | P45452 | 1/20 | 0.70 |
| ▸ | MMP14 | P50281 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729717 | 1.00 | MMP1 (0.70) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8727675 | 0.96 | MMP1 (0.64) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8727681 | 0.96 | MMP1 (0.64) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8733001 | 0.87 | MAPT (0.65) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8733003 | 0.87 | MAPT (0.65) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL9176313 | 0.85 | MMP1 (0.72) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8733294 | 0.80 | MAPT (0.56) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8733295 | 0.80 | MAPT (0.56) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL6886335 | 0.72 | MAPT (0.68) | MMP1MMP2MMP13MMP14MAPT | |
| SCHEMBL8181735 | 0.69 | AKR1B1 (0.73) | MMP1MMP2MMP13MMP14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |