Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436796 | 0.74 | HPGD (0.36) | LMNAALDH1A1HTTRXFP1ALOX15 | |
| SCHEMBL10144166 | 0.72 | ALDH1A1 (0.47) | LMNAALDH1A1HTTKDM4EGLA | |
| SCHEMBL5405571 | 0.71 | ALDH1A1 (0.33) | LMNAALDH1A1HTTKDM4EGLA | |
| SCHEMBL3027067 | 0.71 | HPGD (0.36) | LMNAALDH1A1HTTKDM4EGLA | |
| SCHEMBL14507031 | 0.70 | GABRA1 (0.41) | LMNAALDH1A1HTTRXFP1BACE1 | |
| SCHEMBL9988198 | 0.69 | APOBEC3G (0.37) | LMNAALDH1A1HTTKDM4EGLA | |
| SCHEMBL4800076 | 0.68 | ALOX5 (0.43) | LMNAALDH1A1HTTKDM4ERXFP1 | |
| SCHEMBL7362224 | 0.67 | APOBEC3G (0.61) | LMNAALDH1A1HTTALOX15TSHR | |
| SCHEMBL3842830 | 0.67 | SLC6A2 (0.46) | LMNAALDH1A1HTTKDM4EGLA | |
| SCHEMBL7674655 | 0.67 | HPGD (0.39) | LMNAALDH1A1HTTRXFP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |