Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | GRM5 | P41594 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132140 | 0.84 | GRM5 (0.66) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL30707880 | 0.84 | GRM5 (0.66) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL7601866 | 0.83 | GRM5 (0.56) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL29994376 | 0.83 | GRM5 (0.56) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL852785 | 0.80 | ACHE (0.50) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL182676 | 0.80 | ACHE (0.50) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL30083320 | 0.80 | P4HB (0.55) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL103841 | 0.80 | P4HB (0.55) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL96045 | 0.80 | CA1 (0.53) | ALDH1A1CYP3A4ACHECA1CA2 | |
| SCHEMBL29666208 | 0.80 | ACHE (0.50) | ALDH1A1CYP3A4ACHECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |