Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264574 | 0.83 | SMN1; SMN2 (0.64) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL29200385 | 0.77 | TP53 (0.61) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL11028218 | 0.77 | HTT (0.77) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL5153133 | 0.75 | TP53 (0.59) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL26082853 | 0.75 | MEN1 (0.62) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL17976487 | 0.75 | TP53 (0.59) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL29200433 | 0.75 | SMN1; SMN2 (0.59) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL21810514 | 0.74 | SMN1; SMN2 (0.81) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL17976370 | 0.73 | SMN1; SMN2 (0.55) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL3267386 | 0.72 | CYP1A2 (0.59) | HTTMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | claimed |