Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8733453

C=CCN(CC=C)C(O)=S.N.NC(O)=S

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.40
ALDH1A1 P00352 6/20 0.37
LMNA P02545 3/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
CCR6 P51684 1/20 0.36
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
KDM4E B2RXH2 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30904 0.98 CYP1A2 (0.41) CYP1A2ALDH1A1LMNAHPGDALOX12
SCHEMBL1484098 0.95 CYP1A2 (0.40) CYP1A2ALDH1A1LMNAHPGDALOX12
Hydrochloric Acid SCHEMBL11788098 0.95 CYP1A2 (0.40) CYP1A2ALDH1A1LMNAHPGDALOX12
SCHEMBL2363225 0.95 CYP1A2 (0.40) CYP1A2ALDH1A1LMNAHPGDALOX12
SCHEMBL406319 0.90 CYP1A2 (0.45) CYP1A2ALDH1A1LMNAHPGDALOX12
Hydrochloric Acid SCHEMBL11628599 0.87 CYP1A2 (0.44) CYP1A2ALDH1A1LMNAHPGDALOX12
SCHEMBL325008 0.77 ALDH1A1 (0.41) CYP1A2ALDH1A1LMNAHPGDALOX12
SCHEMBL11415997 0.73 ALDH1A1 (0.38) CYP1A2ALDH1A1LMNAHPGDALOX12
SCHEMBL5979774 0.71 ABCB11 (0.39) CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D
SCHEMBL15212888 0.71 ALDH1A1 (0.37) CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4440867-A Calcined, high surface area, particulate matter, processes using this matter, and admixtures with other agents ENSOTECH, INC. (US) 1984-04-03 US claimed
EP-3666757-A1 PROCESS FOR PREPARING A PIPERIDIN-4-ONE Karl-Franzens-Universität Graz (AT) 2020-06-17 EP disclosed
WO-1998005206-A1 QUATERNARY AMMONIUM SALT COMPOSITIONS, AND METHODS FOR TREATING SUBSTRATES HICKSON INTERNATIONAL PLC (US) 1998-02-12 WO disclosed