Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30904 | 0.98 | CYP1A2 (0.41) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL2363225 | 0.95 | CYP1A2 (0.40) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| Hydrochloric Acid SCHEMBL11788098 | 0.95 | CYP1A2 (0.40) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| Ammonia Solution, Strong SCHEMBL8733453 | 0.95 | CYP1A2 (0.40) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL406319 | 0.90 | CYP1A2 (0.45) | CYP1A2ALDH1A1TSHRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11628599 | 0.87 | CYP1A2 (0.44) | CYP1A2ALDH1A1SMN1; SMN2GRIN2DGRIN3B | |
| SCHEMBL325008 | 0.77 | ALDH1A1 (0.41) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL11415997 | 0.73 | ALDH1A1 (0.38) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL5979774 | 0.71 | ABCB11 (0.39) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D | |
| SCHEMBL15212888 | 0.71 | ALDH1A1 (0.37) | CYP1A2ALDH1A1TSHRSMN1; SMN2GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2683370-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-01-15 | — | — | EP | disclosed |
| US-8575218-B2 | Thiol-containing compounds for the removal of elements from tissues and formulations therefor | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-11-05 | — | — | US | disclosed |
| WO-2012121798-A2 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-09-13 | — | — | WO | disclosed |
| EP-2483239-A2 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011038385-A9 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110160150-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2011-06-30 | — | — | US | disclosed |
| WO-2011038385-A2 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2011-03-31 | — | — | WO | disclosed |
| US-20110076246-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | HALEY BOYD E | 2011-03-31 | — | — | US | disclosed |
| EP-1355883-A2 | NOVEL MULTIDENTATE SULFUR-CONTAINING LIGANDS | The University of Kentucky Research Foundation (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6586600-B2 | For removing metals from soils, water; pollution control; form stable, irreversible ligand-metal precipitates | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2003-07-01 | — | — | US | disclosed |
| US-20020100732-A1 | Novel multidentate sulfur-containing ligands | CHELATOR TECHNOLOGIES, INC. | 2002-08-01 | — | — | US | disclosed |
| WO-2002049967-A2 | NOVEL MULTIDENTATE SULFUR-CONTAINING LIGANDS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160150-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM TISSUES AND FORMULATIONS THEREFOR | SLC39A11, TST, SLC39A14 | CYP1A2 1065/4885ALDH1A1 348/4885TSHR 168/4885 |
| US-20110076246-A1 | THIOL-CONTAINING COMPOUNDS FOR THE REMOVAL OF ELEMENTS FROM CONTAMINATED MILIEU AND METHODS OF USE | TST, MPST, ARSA | CYP1A2 2384/4885ALDH1A1 587/4885TSHR 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.