Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 8/20 | 0.33 |
| ▸ | MAOA | P21397 | 8/20 | 0.33 |
| ▸ | MAOB | P27338 | 8/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113896 | 0.62 | LMNA (0.37) | LMNASLC18A3KDM1AMAOAMAOB | |
| SCHEMBL1838207 | 0.61 | SLC9A1 (0.35) | KDM1AMAOAMAOBADORA3KDM4E | |
| SCHEMBL28495176 | 0.60 | LMNA (0.42) | LMNAMAOAMAOBAOC3TRPA1 | |
| SCHEMBL4112725 | 0.59 | EPHX1 (0.56) | LMNASLC18A3TRPA1EPHX1 | |
| SCHEMBL11959995 | 0.59 | EPHX1 (0.56) | LMNASLC18A3TRPA1EPHX1 | |
| SCHEMBL11981349 | 0.59 | EPHX1 (0.56) | LMNASLC18A3TRPA1EPHX1 | |
| Phenol SCHEMBL11850258 | 0.58 | TDP1 (0.52) | LMNAADORA3AOC3TRPA1 | |
| Phenylpropanol SCHEMBL27340941 | 0.58 | LMNA (0.91) | LMNAAOC3KDM4E | |
| SCHEMBL18533592 | 0.58 | SMN1; SMN2 (0.42) | LMNASLC18A3KDM1AMAOAMAOB | |
| SCHEMBL3377292 | 0.57 | LMNA (0.38) | LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877607-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997027846-A1 | BIPHENYL COMPOUNDS AND USE THEREOF AS OESTROGENIC AGENTS | HOECHST MARION ROUSSEL (FR) | 1997-08-07 | — | — | WO | disclosed |