Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234087 | 0.91 | SLC6A4 (0.46) | OPRM1OPRL1OPRK1OPRD1SLC6A4 | |
| SCHEMBL9384128 | 0.86 | OPRM1 (0.48) | LMNAOPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL13849911 | 0.85 | OPRM1 (0.44) | LMNAOPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL14402615 | 0.85 | OPRM1 (0.44) | LMNAOPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL3377292 | 0.83 | LMNA (0.38) | LMNAOPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL28400428 | 0.81 | SLC6A4 (0.37) | LMNAOPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL20876291 | 0.77 | CYP2D6 (0.42) | OPRM1OPRL1OPRK1OPRD1CYP2D6 | |
| SCHEMBL13307869 | 0.76 | CYP2C19 (0.40) | LMNAMAOAMAOBTAAR1DPP4 | |
| SCHEMBL2438892 | 0.76 | CYP2C19 (0.40) | LMNAMAOAMAOBTAAR1DPP4 | |
| SCHEMBL4576233 | 0.72 | CYP2D6 (0.45) | OPRM1OPRL1OPRK1OPRD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256314-B | Preparation method of beta-aryl ketone compound and product thereof | 南京林业大学 | 2020-12-15 | — | — | CN | disclosed |