Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.49 |
| ▸ | RARG | P13631 | 11/20 | 0.49 |
| ▸ | RARA | P10276 | 11/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.49 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 9/20 | 0.49 |
| ▸ | RXRB | P28702 | 6/20 | 0.49 |
| ▸ | RXRG | P48443 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225011 | 0.81 | RARG (0.69) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7225007 | 0.81 | RARG (0.69) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL7225013 | 0.81 | RARG (0.69) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL28133361 | 0.79 | RARB (0.45) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL4317998 | 0.79 | KMT2A (0.68) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8771910 | 0.77 | TDP2 (0.43) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL8462116 | 0.76 | POLB (0.47) | RARBRARGRARACYP26A1RXRA | |
| SCHEMBL14782138 | 0.75 | RXRA (0.70) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL1156918 | 0.74 | RARB (0.47) | RARBRARGRARACYP26A1CYP26B1 | |
| SCHEMBL29827631 | 0.74 | RARB (0.81) | RARBRARGRARACYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869782-A2 | METHODS OF TREATMENT WITH COMPOUNDS HAVING RAR $g(a)? RECEPTOR SPECIFIC OR SELECTIVE ACTIVITY | Vision Pharmaceuticals L.P. (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024116-A2 | METHODS OF TREATMENT WITH COMPOUNDS HAVING RARα RECEPTOR SPECIFIC OR SELECTIVE ACTIVITY | VISION PHARMACEUTICALS L.P. (US) | 1997-07-10 | — | — | WO | disclosed |