Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480306 | 0.77 | ACHE (0.41) | ACHES100A4CSNK2A2CSNK2A1PBRM1 | |
| SCHEMBL8845677 | 0.72 | ACHE (0.62) | ACHEMAOBCYP19A1CSNK2A2CSNK2A1 | |
| SCHEMBL8903475 | 0.71 | ACHE (0.40) | ACHES100A4TSHR | |
| SCHEMBL8904346 | 0.69 | PARP1 (0.36) | ACHES100A4CSNK2A2CSNK2A1STAT3 | |
| Hydrochloric Acid SCHEMBL8903529 | 0.68 | PARP1 (0.35) | ACHES100A4STAT3 | |
| SCHEMBL20368206 | 0.66 | ACHE (0.48) | ACHEMAOBCYP19A1S100A4KDM4E | |
| SCHEMBL9372008 | 0.66 | ACHE (0.48) | ACHEMAOBCYP19A1S100A4KDM4E | |
| SCHEMBL9367273 | 0.66 | ACHE (0.48) | ACHEMAOBCYP19A1S100A4KDM4E | |
| SCHEMBL31326549 | 0.66 | ACHE (0.48) | ACHEMAOBCYP19A1S100A4KDM4E | |
| SCHEMBL181579 | 0.66 | ACHE (0.48) | ACHEMAOBCYP19A1S100A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728773-B1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEM CORP (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0693502-B1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEM CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5594081-A | METALLOCENES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0728773-A1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0693502-A1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |