Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 2/20 | 0.34 |
| ▸ | LDHB | P07195 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12205326 | 0.79 | ACHE (0.36) | ACHEPIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL8734160 | 0.77 | ACHE (0.38) | ACHEPBRM1S100A4CSNK2A2CSNK2A1 | |
| SCHEMBL8903475 | 0.75 | ACHE (0.40) | ACHES100A4CA1CA2LDHA | |
| SCHEMBL31383949 | 0.75 | PIM1 (0.34) | ACHEPIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL30356308 | 0.75 | KIF11 (0.39) | PIM1CSNK1A1CDK5ROCK1DYRK1A | |
| SCHEMBL1699423 | 0.74 | PIM1 (0.43) | ACHEPIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL30338328 | 0.74 | KIF11 (0.36) | KIF11 | |
| SCHEMBL7928973 | 0.73 | CYP1A2 (0.38) | ACHELDHALDHBTSHRBRD4 | |
| SCHEMBL8904346 | 0.73 | PARP1 (0.36) | ACHES100A4CSNK2A2CSNK2A1STAT3 | |
| SCHEMBL1453605 | 0.72 | ACHE (0.66) | ACHEPIM1CSNK1A1CDK5ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590929-B1 | SPIRO COMPOUND AND USE THEREOF | MEDSHINE DISCOVERY INC (CN) | 2021-09-15 | — | — | EP | disclosed |
| EP-1963347-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-7550544-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550544-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550544-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7446216-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446216-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-7446216-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-11-04 | — | — | US | disclosed |
| EP-1963347-A1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1833858-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2007-09-19 | — | — | EP | disclosed |
| EP-0693502-B1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEM CORP (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5639911-A | Hydrazones | CIBA-GEIGY CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5594081-A | METALLOCENES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0728773-A1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0693502-A1 | Catalyst component for the polymerization of alpha-olefins and a process for preparing alpha-olefin polymers with use of same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5461076-A | Inhibitors of S-adenosylmethionine decarboxylase; antitumor agents | NOVARTIS CORPORATION | 1995-10-24 | — | — | US | disclosed |
| EP-0456133-B1 | Hydrazones | CIBA GEIGY AG (CH) | 1995-03-15 | — | — | EP | disclosed |
| US-5395855-A | Antitumor agents | CIBA-GEIGY CORPORATION (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0538193-A2 | Condensed cycloaliphatir-amidino-hydrazon salts as S-adenosylmethionin decarboxylase inhibitors | CIBA-GEIGY AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0456133-A1 | Hydrazones | CIBA-GEIGY AG (CH) | 1991-11-13 | — | — | EP | disclosed |