Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | MDM4 | O15151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854308 | 0.85 | MDM4 (0.37) | CHRM3MDM4TP53FABP5CHRNB2 | |
| SCHEMBL8732445 | 0.84 | FABP5 (0.37) | CHRM3MDM4TP53FABP5CHRNB2 | |
| SCHEMBL6849920 | 0.81 | CHRM3 (0.46) | CHRM3MDM4TP53FABP5CHRNB2 | |
| SCHEMBL8729229 | 0.72 | LMNA (0.39) | MDM4TP53FABP5CHRNB2CHRNA4 | |
| SCHEMBL6853795 | 0.72 | LMNA (0.39) | MDM4TP53FABP5CHRNB2CHRNA4 | |
| SCHEMBL8729183 | 0.72 | LMNA (0.39) | MDM4TP53FABP5CHRNB2CHRNA4 | |
| SCHEMBL8609022 | 0.71 | FABP5 (0.43) | MDM4TP53FABP5MEN1KMT2A | |
| SCHEMBL6858012 | 0.69 | PIN1 (0.36) | CHRM3MDM4TP53FABP5MEN1 | |
| SCHEMBL10118380 | 0.68 | SLC6A11 (0.48) | CHRM3TP53FABP5MEN1KMT2A | |
| SCHEMBL6858060 | 0.67 | FABP5 (0.37) | MDM4TP53FABP5KMT2AFABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |