SCHEMBL8734435

SCHEMBL8734435

C=CC(=O)OCCCC.C=CN1CCCCCC1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.55
HPGD P15428 3/20 0.55
ALDH1A1 P00352 5/20 0.41
CYP3A4 P08684 1/20 0.41
ATM Q13315 1/20 0.40
TP53 P04637 3/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
NFKB1 P19838 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
THRB P10828 3/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
PRKCA P17252 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11674208 0.95 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL2196152 0.90 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL10878664 0.87 ATM (0.53) TSHRHPGDATMMAPTSMN1; SMN2
SCHEMBL11456720 0.87 ATM (0.53) TSHRHPGDATMMAPTSMN1; SMN2
Butyl Fumarate SCHEMBL11456721 0.83 HCAR2 (0.57) TSHRHPGDATMMAPTSMN1; SMN2
Acrylic Acid Ethyl Ester SCHEMBL251480 0.81 ALDH1A1 (0.37) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL10792166 0.81 TSHR (0.42) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL28333123 0.81 TSHR (0.55) TSHRALDH1A1TP53MAPTKMT2A
Acrylic Acid Ethyl Ester SCHEMBL11276113 0.80 TSHR (0.41) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL2852122 0.80 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617974-B2 Partable laminate and method for parting long-term structural bonds TESA SE (DE) 2026-05-05 US disclosed
US-12540258-B2 Light-curing reactive adhesive film TESA SE (DE) 2026-02-03 US disclosed
EP-4159775-B1 PHOTO-SETTING REACTIVE ADHESIVE FILM TESA SE (DE) 2023-09-13 EP disclosed
US-20230279270-A1 PARTABLE LAMINATE AND METHOD FOR PARTING LONG-TERM STRUCTURAL BONDS TESA SE (DE) 2023-09-07 US disclosed
CN-116691082-A Separable laminate and method for separating long-term structural bonds 德莎欧洲股份公司 2023-09-05 CN disclosed
US-20230117532-A1 LIGHT-CURING REACTIVE ADHESIVE FILM TESA SE (DE) 2023-04-20 US disclosed
EP-4159775-A1 PHOTO-SETTING REACTIVE ADHESIVE FILM tesa SE (DE) 2023-04-05 EP disclosed
CN-115895457-A Photocurable reactive adhesive film 德莎欧洲股份公司 2023-04-04 CN disclosed
EP-0729494-B1 PRESSURE SENSITIVE THERMOSETTING ADHESIVES MINNESOTA MINING & MFG (US) 1998-08-12 EP disclosed
EP-0729494-A1 PRESSURE SENSITIVE THERMOSETTING ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-04 EP disclosed
WO-1995013328-A1 PRESSURE SENSITIVE THERMOSETTING ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-18 WO disclosed
EP-0130080-B1 PRESSURE SENSITIVE ADHESIVE Johnson & Johnson Products Inc. (US) 1988-05-18 EP disclosed
EP-0130080-A1 Pressure sensitive adhesive Johnson & Johnson Products Inc. (US) 1985-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540258-B2 Light-curing reactive adhesive film ICAM1, MACF1, CDH1 TSHR 4668/4885HPGD 932/4885ALDH1A1 107/4885
US-12617974-B2 Partable laminate and method for parting long-term structural bonds MGMT, EPCAM, TMPO TSHR 4471/4885HPGD 970/4885ALDH1A1 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.