SCHEMBL8734497

SCHEMBL8734497

CCC(C)COC(=O)C(=Cc1ccc(OC)cc1)C(=O)OCC(C)CC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.48
MAPT P10636 6/20 0.48
MEN1 O00255 5/20 0.48
LMNA P02545 4/20 0.48
NPSR1 Q6W5P4 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
S1PR4 O95977 1/20 0.48
S1PR1 P21453 1/20 0.48
MAPK1 P28482 1/20 0.48
NR1H4 Q96RI1 1/20 0.46
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
HSP90AA1 P07900 2/20 0.43
HPGD P15428 1/20 0.43
TAS1R3 Q7RTX0 2/20 0.43
TAS1R1 Q7RTX1 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
GSK3B P49841 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23204862 0.96 KMT2A (0.45) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL21514715 0.96 KMT2A (0.45) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL19450577 0.94 TDP1 (0.44) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL20050122 0.92 MAPT (0.44) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL17576317 0.89 TDP1 (0.61) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL12869956 0.88 NR1H4 (0.51) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL12869955 0.86 MAPT (0.50) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL17576050 0.86 MEN1 (0.54) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL13241269 0.85 KMT2A (0.66) KMT2AMAPTMEN1LMNANPSR1
SCHEMBL22365540 0.84 MAPT (0.41) KMT2AMAPTMEN1LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793742-B2 Mixtures of cosmetic UV absorbers BASF SE (DE) 2023-10-24 US disclosed
US-11793742-B2 Mixtures of cosmetic UV absorbers BASF SE (DE) 2023-10-24 US disclosed
EP-3191075-B1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2023-02-15 EP disclosed
EP-3523350-B1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION BASF SE (DE) 2022-12-07 EP disclosed
US-11046814-B2 Ultraviolet radiation absorbing polymer composition BASF SE (DE) 2021-06-29 US disclosed
EP-3305279-B1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION JOHNSON & JOHNSON CONSUMER INC (US) 2021-04-07 EP disclosed
US-10874597-B2 Ultraviolet radiation absorbing polymer composition JOHNSON & JOHNSON CONSUMER INC. (US) 2020-12-29 US disclosed
US-20200299459-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION BASF SE (DE) 2020-09-24 US disclosed
EP-3128993-B1 MIXTURES OF COSMETIC UV ABSORBERS BASF SE (DE) 2020-08-26 EP disclosed
US-20200155432-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION KENVUE BRANDS LLC 2020-05-21 US disclosed
US-9364418-B2 Water-resistant cosmetic formulations comprising a hydrophobically modified vinylpyrrolidone copolymer BASF SE (DE) 2016-06-14 US disclosed
US-9364418-B2 Water-resistant cosmetic formulations comprising a hydrophobically modified vinylpyrrolidone copolymer BASF SE (DE) 2016-06-14 US disclosed
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS BASF SE (DE) 2016-03-10 US disclosed
WO-2016012586-A1 SUNSCREEN FORMULATIONS OPTIMIZED FOR THE FORMATION OF VITAMIN D BASF SE (DE) 2016-01-28 WO disclosed
US-20120276027-A1 WATER-RESISTANT COSMETIC FORMULATIONS COMPRISING A HYDROPHOBICALLY MODIFIED VINYLPYRROLIDONE COPOLYMER BASF SE (DE) 2012-11-01 US disclosed
US-20120276027-A1 WATER-RESISTANT COSMETIC FORMULATIONS COMPRISING A HYDROPHOBICALLY MODIFIED VINYLPYRROLIDONE COPOLYMER BASF SE (DE) 2012-11-01 US disclosed
US-20120128745-A1 BENZYLIDENE MALONATES BASF SE (DE) 2012-05-24 US disclosed
US-20120128745-A1 BENZYLIDENE MALONATES BASF SE (DE) 2012-05-24 US disclosed
WO-2011086073-A2 WATER-RESISTANT COSMETIC FORMULATIONS COMPRISING A HYDROPHOBICALLY MODIFIED VINYLPYRROLIDONE COPOLYMER BASF SE (DE) 2011-07-21 WO disclosed
WO-2010136360-A2 BENZYLIDENE MALONATES BASF SE (DE) 2010-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874597-B2 Ultraviolet radiation absorbing polymer composition ERCC4, ERCC5, ERCC1 KMT2A 4518/4885MAPT 204/4885MEN1 1945/4885
US-20200299459-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION GGCT, UGT1A3, B3GAT3 KMT2A 3299/4885MAPT 358/4885MEN1 2310/4885
US-20160067158-A1 AGENTS CONTAINING LARGE QUANTITIES OF UV STABILIZERS ERCC5, ERCC1, TTPA KMT2A 3804/4885MAPT 425/4885MEN1 4242/4885
US-20120128745-A1 BENZYLIDENE MALONATES TERT, REL, MGMT KMT2A 4071/4885MAPT 3983/4885MEN1 120/4885
US-20120276027-A1 WATER-RESISTANT COSMETIC FORMULATIONS COMPRISING A HYDROPHOBICALLY MODIFIED VINYLPYRROLIDONE COPOLYMER TP53, PWWP2B, ALAD KMT2A 3448/4885MAPT 2832/4885MEN1 2342/4885
US-20200155432-A1 ULTRAVIOLET RADIATION ABSORBING POLYMER COMPOSITION ERCC4, ERCC5, ERCC1 KMT2A 4518/4885MAPT 204/4885MEN1 1945/4885
US-11793742-B2 Mixtures of cosmetic UV absorbers BTD, TMSB10, TH KMT2A 3255/4885MAPT 2781/4885MEN1 1967/4885
US-11046814-B2 Ultraviolet radiation absorbing polymer composition GGCT, B3GAT3, UGT1A3 KMT2A 3636/4885MAPT 720/4885MEN1 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.