Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764757 | 0.81 | PTPN5 (0.36) | NFE2L2PTPN5MAOBATMKDM4E | |
| SCHEMBL8729840 | 0.80 | PTPN5 (0.36) | NFE2L2PTPN5MAOBATMKDM4E | |
| SCHEMBL8854736 | 0.79 | NFE2L2 (0.42) | NFE2L2MAOBATMLMNAKMT2A | |
| SCHEMBL8762778 | 0.77 | ATM (0.37) | NFE2L2PTPN5MAOBATMKDM4E | |
| SCHEMBL8854731 | 0.76 | NFE2L2 (0.40) | NFE2L2MAOBATMLMNAKMT2A | |
| SCHEMBL8854420 | 0.75 | NFE2L2 (0.36) | NFE2L2MAOBATMLMNAKMT2A | |
| SCHEMBL8740250 | 0.74 | NFE2L2 (0.43) | NFE2L2MAOBATMKDM4ELMNA | |
| SCHEMBL8764036 | 0.73 | SMN1; SMN2 (0.32) | NFE2L2ATMSMN1; SMN2 | |
| SCHEMBL3598103 | 0.73 | NFE2L2 (0.42) | NFE2L2MAOBKMT2A | |
| SCHEMBL31172692 | 0.73 | NFE2L2 (0.42) | NFE2L2MAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699390-B1 | Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use | ROHM & HAAS (US) | 1998-10-07 | — | — | EP | claimed |