Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729840 | 0.91 | PTPN5 (0.36) | PTPN5ATMMAOBNFE2L2SMN1; SMN2 | |
| SCHEMBL8762778 | 0.88 | ATM (0.37) | PTPN5ATMMAOBNFE2L2SMN1; SMN2 | |
| SCHEMBL8764415 | 0.85 | MEN1 (0.33) | ATMKDM4EKMT2AMEN1TSHR | |
| SCHEMBL8729845 | 0.83 | SMN1; SMN2 (0.33) | ATMMAOBNFE2L2SMN1; SMN2LMNA | |
| SCHEMBL8729873 | 0.83 | ATM (0.34) | ATMMAOBNFE2L2SMN1; SMN2LMNA | |
| SCHEMBL8731887 | 0.82 | NFE2L2 (0.35) | ATMMAOBNFE2L2SMN1; SMN2LMNA | |
| SCHEMBL8764036 | 0.82 | SMN1; SMN2 (0.32) | ATMNFE2L2SMN1; SMN2MAPTHPGD | |
| SCHEMBL8734572 | 0.81 | NFE2L2 (0.38) | PTPN5ATMMAOBNFE2L2SMN1; SMN2 | |
| SCHEMBL8764702 | 0.80 | SMN1; SMN2 (0.32) | ATMMAOBNFE2L2SMN1; SMN2LMNA | |
| SCHEMBL8729954 | 0.80 | CTSS (0.34) | ATMMAOBNFE2L2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511826-B1 | Phosphosulfonate herbicides | ROHM & HAAS (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0511826-A2 | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1992-11-04 | — | — | EP | claimed |