Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598103 | 0.85 | NFE2L2 (0.42) | NFE2L2MAOBARGAAKMT2A | |
| SCHEMBL6630905 | 0.85 | NFE2L2 (0.42) | NFE2L2LMNAMAOBARGAA | |
| SCHEMBL8854736 | 0.85 | NFE2L2 (0.42) | NFE2L2LMNAMAOBARGAA | |
| SCHEMBL31172692 | 0.85 | NFE2L2 (0.42) | NFE2L2MAOBARGAAKMT2A | |
| SCHEMBL8854731 | 0.82 | NFE2L2 (0.40) | NFE2L2LMNAMAOBARGAA | |
| Hydrochloric Acid SCHEMBL27480628 | 0.82 | NFE2L2 (0.35) | NFE2L2KDM4ELMNANPSR1NR1H2 | |
| SCHEMBL25044629 | 0.81 | CA2 (0.48) | KDM4EMITFLMNAHPGDHTT | |
| SCHEMBL30839044 | 0.79 | SLC22A12 (0.36) | NFE2L2NR1H2SLC22A12NR1H3 | |
| SCHEMBL17038538 | 0.77 | AR (0.42) | NFE2L2KDM4ELMNAMAOBAR | |
| SCHEMBL8854433 | 0.77 | NFE2L2 (0.38) | NFE2L2LMNAMAOBARGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616789-A | CHEMICAL INTERMEDIATE FOR 2-PHENYLPYRIDAZINE HERBICIDE | MONSANTO COMPANY (US) | 1997-04-01 | — | — | US | disclosed |