SCHEMBL8734639

SCHEMBL8734639

O=[PH](O)COS(=O)(=O)c1ccc(F)cc1C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.37
EPHX2 P34913 1/20 0.35
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
HSD11B1 P28845 7/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
TRPV4 Q9HBA0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854418 0.84 IDO1 (0.35) IDO1EPHX2CNR1CNR2HSD11B1
SCHEMBL8732244 0.81 MEN1 (0.43) HSD11B1
SCHEMBL8732790 0.80
SCHEMBL8732656 0.80 PKM (0.37)
SCHEMBL8731772 0.78 IDO1 (0.37) IDO1EPHX2CNR1CNR2HSD11B1
SCHEMBL27483442 0.75 TRPV4 (0.38) IDO1EPHX2CNR1CNR2HSD11B1
SCHEMBL8854586 0.75 IDO1 (0.37) IDO1EPHX2CNR1CNR2HSD11B1
SCHEMBL8854592 0.73 IDO1 (0.35) IDO1EPHX2CNR1CNR2HSD11B1
SCHEMBL8854424 0.73 TRPV4 (0.35) IDO1EPHX2CNR1CNR2HSD11B1
SCHEMBL8731975 0.73 HSD11B1 (0.33) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed