Pirimicarb

Pirimicarb

SCHEMBL8734699

CNC(=O)Oc1cccc2c1OC(C)(C)O2.Cc1nc(N(C)C)nc(OC(=O)N(C)C)c1C

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.38
PGR P06401 1/20 0.34
GAA P10253 1/20 0.34
PTGS1 P23219 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NCEH1 Q6PIU2 1/20 0.32
BCHE P06276 2/20 0.32
ACHE P22303 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bendiocarb SCHEMBL27847663 0.79 ALDH1A1 (1.00) ALDH1A1LMNAPGRGAAPTGS1
Bendiocarb SCHEMBL3954562 0.79 ALDH1A1 (1.00) ALDH1A1LMNAPGRGAAPTGS1
Bendiocarb SCHEMBL22080 0.79 ALDH1A1 (1.00) ALDH1A1LMNAPGRGAAPTGS1
Bendiocarb SCHEMBL7533636 0.78 ALDH1A1 (0.92) ALDH1A1LMNAPGRGAAPTGS1
Bendiocarb SCHEMBL10378552 0.75 ALDH1A1 (0.92) ALDH1A1LMNAPGRGAAPTGS1
Pirimicarb SCHEMBL5526018 0.74 NPSR1 (0.41) ALDH1A1NPSR1PGRGAAPTGS1
Bendiocarb SCHEMBL28299657 0.74 ALDH1A1 (0.90) ALDH1A1LMNAPGRGAAPTGS1
Bendiocarb SCHEMBL1071011 0.73 ALDH1A1 (0.81) ALDH1A1LMNAPGRGAAPTGS1
Pirimicarb SCHEMBL29407096 0.73 NPSR1 (0.46) ALDH1A1LMNANPSR1HSD17B10NCEH1
Pirimicarb SCHEMBL26523 0.73 NPSR1 (0.46) ALDH1A1LMNANPSR1HSD17B10NCEH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998017277-A1 AMIDINE COMPOUNDS FOR USE IN SYSTEMIC TREATING ECTO AND/OR ENDO PARASITIC DISEASES VIRBAC S.A. (FR) 1998-04-30 WO claimed
EP-0836851-A1 Amidine compounds for use in treating ecto or endo parasitic diseases and systemic parasite control compositions VIRBAC S.A. (FR) 1998-04-22 EP claimed
WO-1998017277-A1 AMIDINE COMPOUNDS FOR USE IN SYSTEMIC TREATING ECTO AND/OR ENDO PARASITIC DISEASES VIRBAC S.A. (FR) 1998-04-30 WO disclosed
EP-0836851-A1 Amidine compounds for use in treating ecto or endo parasitic diseases and systemic parasite control compositions VIRBAC S.A. (FR) 1998-04-22 EP disclosed