Pirimicarb

Pirimicarb

SCHEMBL5526018

CCSCc1ccccc1OC(=O)NC.Cc1nc(N(C)C)nc(OC(=O)N(C)C)c1C

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 1/20 0.36
NCEH1 Q6PIU2 6/20 0.34
ALDH1A1 P00352 2/20 0.34
PGR P06401 1/20 0.34
GAA P10253 1/20 0.34
PTGS1 P23219 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX5 P09917 1/20 0.32
ACHE P22303 1/20 0.32
TSPO P30536 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethiofencarb SCHEMBL74938 0.78 ALDH1A1 (0.49) TSHRALDH1A1PGRGAAPTGS1
Ethiofencarb SCHEMBL29449861 0.78 ALDH1A1 (0.49) TSHRALDH1A1PGRGAAPTGS1
Ethiofencarb SCHEMBL6738022 0.78 ALDH1A1 (0.49) TSHRALDH1A1PGRGAAPTGS1
Ethiofencarb SCHEMBL7528780 0.76 ALDH1A1 (0.46) TSHRALDH1A1PGRGAAPTGS1
Pirimicarb SCHEMBL8734699 0.74 ALDH1A1 (0.62) NPSR1NCEH1ALDH1A1PGRGAA
Pirimicarb SCHEMBL6738287 0.73 NPSR1 (0.46) NPSR1NCEH1ALDH1A1HSD17B10TSPO
Pirimicarb SCHEMBL29407096 0.73 NPSR1 (0.46) NPSR1NCEH1ALDH1A1HSD17B10TSPO
Pirimicarb SCHEMBL26523 0.73 NPSR1 (0.46) NPSR1NCEH1ALDH1A1HSD17B10TSPO
SCHEMBL11796469 0.72 ALDH1A1 (0.46) TSHRALDH1A1PGRGAAPTGS1
Ethiofencarb SCHEMBL28835316 0.72 TSHR (0.37) TSHRALDH1A1PGRGAAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070142439-A1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA LTD. (JP) 2007-06-21 US claimed
EP-1073513-B1 IMPROVED EXTRUSION PROCESS BASF CORP (US) 2003-08-27 EP disclosed
US-6273929-B1 Extrusion process BASF CORPORATION 2001-08-14 US disclosed
EP-1073513-A1 IMPROVED EXTRUSION PROCESS BASF CORPORATION (US) 2001-02-07 EP disclosed
WO-1999055452-A1 IMPROVED EXTRUSION PROCESS BASF CORPORATION (US) 1999-11-04 WO disclosed
US-5622658-A MIXING GRANULES; EXTRUSING MIXTURE; ROLLING TO BREAK GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1997-04-22 US disclosed
US-5443764-A Water-dispersible granules ICI AUSTRALIA OPERATIONS PROPIETARY LIMITED (AU) 1995-08-22 US disclosed
EP-0321527-B1 WATER DISPERSIBLE GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1992-08-12 EP disclosed
EP-0321527-A4 WATER DISPERSIBLE GRANULES. ICI AUSTRALIA OPERATIONS (AU) 1989-07-24 EP disclosed
EP-0321527-A1 WATER DISPERSIBLE GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1989-06-28 EP disclosed
WO-1989000079-A1 WATER DISPERSIBLE GRANULES ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1989-01-12 WO disclosed
EP-0146748-B1 ORGANOPHOSPHORUS COMPOUND, PROCESS FOR ITS PREPARATION AND INSECTICIDAL, MITICIDAL OR NEMATICIDAL COMPOSITION CONTAINING IT ISHIHARA SANGYO KAISHA, LTD. (JP) 1988-05-04 EP disclosed
US-4590182-A Organophosphorus compound and insecticidal, miticidal or nematicidal composition containing it ISHIHARA SANGYO KAISHA LTD. (JP) 1986-05-20 US disclosed
EP-0146748-A1 Organophosphorus compound, process for its preparation and insecticidal, miticidal or nematicidal composition containing it ISHIHARA SANGYO KAISHA, LTD. (JP) 1985-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142439-A1 PESTICIDAL COMPOSITION DDT, PRDX1, PRDX6 NPSR1 985/4885TSHR 269/4885NCEH1 3124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.