Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736833 | 0.85 | SLC18A3 (0.64) | SLC18A3GRIN2BDRD2SIGMAR1 | |
| SCHEMBL8734717 | 0.80 | DRD2 (0.41) | SLC18A3DRD2 | |
| SCHEMBL8736265 | 0.78 | SLC18A3 (0.55) | SLC18A3GRIN2BDRD2SIGMAR1 | |
| SCHEMBL8736298 | 0.77 | SLC18A3 (1.00) | SLC18A3GRIN2BMEN1KMT2ASIGMAR1 | |
| SCHEMBL8937871 | 0.77 | SLC18A3 (0.76) | SLC18A3GRIN2BMEN1KMT2AGAA | |
| SCHEMBL9340787 | 0.72 | SLC18A3 (0.40) | SLC18A3DRD2 | |
| SCHEMBL10600104 | 0.71 | SLC18A3 (1.00) | SLC18A3DRD2 | |
| SCHEMBL11865781 | 0.71 | SLC18A3 (0.62) | SLC18A3GRIN2BMEN1KMT2AGAA | |
| SCHEMBL152587 | 0.69 | DRD2 (0.81) | SLC18A3DRD2MEN1KMT2ASIGMAR1 | |
| SCHEMBL11154057 | 0.69 | SLC18A3 (0.64) | SLC18A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721243-A | ANTICHOLINERGIC AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0576611-A4 | RADIOPHARMACEUTICAL AGENTS FOR THE DETECTION OF ALZHEIMER'S DISEASE | UNIV MINNESOTA (US) | 1996-01-24 | — | — | EP | disclosed |
| US-5358712-A | For binding to receptors when monitoring for cholinergic innervation in living brains, detection of Alzheimer*s disease | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0576611-A1 | RADIOPHARMACEUTICAL AGENTS FOR THE DETECTION OF ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016239-A1 | RADIOPHARMACEUTICAL AGENTS FOR THE DETECTION OF ALZHEIMER'S DISEASE | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1992-10-01 | — | — | WO | disclosed |