Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736265 | 0.75 | SLC18A3 (0.55) | SLC18A3DRD2KCNH2 | |
| SCHEMBL8734717 | 0.74 | DRD2 (0.41) | SLC18A3DRD2OPRM1KCNH2HRH3 | |
| SCHEMBL8734715 | 0.72 | SLC18A3 (0.62) | SLC18A3DRD2 | |
| SCHEMBL8736833 | 0.69 | SLC18A3 (0.64) | SLC18A3DRD2 | |
| Hydrochloric Acid SCHEMBL4692281 | 0.68 | KCNH2 (0.45) | SLC18A3DRD2OPRM1CCR5PRCP | |
| SCHEMBL9523607 | 0.68 | OPRM1 (0.56) | SLC18A3DRD2OPRM1CCR5HRH3 | |
| SCHEMBL2661616 | 0.66 | KCNH2 (0.56) | SLC18A3DRD2OPRM1CCR5KCNH2 | |
| SCHEMBL7669605 | 0.65 | DRD3 (0.36) | DRD2KCNH2HRH3HTR1ADRD1 | |
| SCHEMBL7060188 | 0.65 | SLC18A3 (0.50) | SLC18A3DRD2CCR5KCNH2HRH3 | |
| SCHEMBL9523741 | 0.65 | OPRM1 (0.55) | SLC18A3DRD2OPRM1CCR5PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358712-A | For binding to receptors when monitoring for cholinergic innervation in living brains, detection of Alzheimer*s disease | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-10-25 | — | — | US | disclosed |