Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734715 | 0.80 | SLC18A3 (0.62) | DRD2SLC18A3 | |
| SCHEMBL9523607 | 0.76 | OPRM1 (0.56) | DRD2SLC18A3OPRM1OPRL1OPRD1 | |
| SCHEMBL9340787 | 0.74 | SLC18A3 (0.40) | DRD2SLC18A3OPRM1KCNH2HRH3 | |
| SCHEMBL8736833 | 0.74 | SLC18A3 (0.64) | DRD2SLC18A3ADRA1DADRA1AADRA1B | |
| SCHEMBL9523741 | 0.73 | OPRM1 (0.55) | DRD2SLC18A3OPRM1OPRL1OPRD1 | |
| SCHEMBL9521516 | 0.72 | SLC18A3 (0.54) | DRD2SLC18A3OPRM1OPRL1OPRD1 | |
| SCHEMBL27452831 | 0.69 | SLC18A3 (0.49) | DRD2SLC18A3OPRM1KCNH2HRH3 | |
| SCHEMBL7402938 | 0.68 | OPRM1 (0.52) | DRD2OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL8736265 | 0.68 | SLC18A3 (0.55) | DRD2SLC18A3KCNH2ADRA1DADRA1A | |
| SCHEMBL19564583 | 0.67 | DRD2 (0.53) | DRD2SLC18A3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721243-A | ANTICHOLINERGIC AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-02-24 | — | — | US | disclosed |