Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610969 | 0.92 | L3MBTL1 (0.40) | MAPTTSHRTDP1HSD17B10CYP3A4 | |
| SCHEMBL4612123 | 0.78 | ACHE (0.36) | MAPTTSHRTDP1HSD17B10CYP3A4 | |
| SCHEMBL4609957 | 0.77 | CES1 (0.42) | MAPTTSHRTDP1HSD17B10CYP3A4 | |
| SCHEMBL4612216 | 0.75 | LMNA (0.40) | MAPTTDP1HSD17B10CYP2C19L3MBTL1 | |
| SCHEMBL4611540 | 0.73 | CYP1A2 (0.43) | MAPTTSHRHSD17B10CYP3A4CYP2C19 | |
| SCHEMBL4611412 | 0.72 | CES1 (0.38) | MAPTTSHRTDP1HSD17B10CYP3A4 | |
| SCHEMBL18177970 | 0.71 | L3MBTL1 (0.39) | MAPTTDP1HSD17B10CYP2C19L3MBTL1 | |
| Benzoic Acid SCHEMBL2471038 | 0.66 | TSHR (0.74) | MAPTTSHRTDP1HSD17B10CYP3A4 | |
| Benzamide SCHEMBL28244650 | 0.65 | MAPT (0.73) | MAPTTSHRTDP1HSD17B10CYP3A4 | |
| Benzamide SCHEMBL28664785 | 0.64 | PARP1 (0.94) | MAPTTSHRTDP1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723558-A | MONOMERS OR MEDICAL MATERIAL, BIOSENSORS AND COSMETICS | NOF CORPORATION (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0790252-A1 | FUMARIC ACID DERIVATIVE AND POLYMER THEREOF | NOF CORPORATION (JP) | 1997-08-20 | — | — | EP | disclosed |