SCHEMBL11358136

SCHEMBL11358136

O=C(Oc1ccccc1)c1ccccc1-c1cc2ccccc2[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.51
MAPT P10636 6/20 0.51
TDP1 Q9NUW8 2/20 0.51
HPGD P15428 4/20 0.48
ALDH1A1 P00352 4/20 0.48
RAB9A P51151 3/20 0.48
NPSR1 Q6W5P4 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CHEK1 O14757 1/20 0.48
KDR P35968 1/20 0.48
PDGFRB P09619 4/20 0.47
PDGFRA P16234 4/20 0.47
NR4A2 P43354 1/20 0.47
HSD17B10 Q99714 3/20 0.46
ALOX15 P16050 2/20 0.46
P2RY1 P47900 1/20 0.46
NPC1 O15118 2/20 0.45
DAO P14920 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734933 0.83 KDM4E (0.57) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL27437769 0.82 KDR (0.56) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL4623053 0.78 ESR1 (0.53) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL11365957 0.78 KDR (0.54) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL31310116 0.78 KDR (0.54) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL28906323 0.78 KDR (0.54) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL2860216 0.78 KDR (0.54) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL69537 0.77 HSD17B10 (0.68) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL29736523 0.76 RAB9A (0.53) KDM4EMAPTTDP1HPGDALDH1A1
SCHEMBL28304567 0.76 KDM4E (0.64) KDM4EMAPTHPGDALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4308194-A Heterocyclic benzoate ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1981-12-29 US disclosed
US-4075220-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4065427-A Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1977-12-27 US disclosed
US-4000148-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-12-28 US disclosed
US-3957813-A BENZOXAZOLYL PHENYL AROMATIC ESTER COMPOUNDS AND THEIR USE AS ULTRAVIOLET STABILIZERS IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1976-05-18 US disclosed