SCHEMBL134038

SCHEMBL134038

Oc1c(Cl)c(F)nc(F)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8735431 0.86 MEN1 (0.34) HPGDTSHRHSD17B10MEN1ALDH1A1
SCHEMBL9787166 0.76 MEN1 (0.32) TSHRMEN1ALDH1A1KMT2A
SCHEMBL17302195 0.75 MEN1 (0.30) HPGDTSHRHSD17B10MEN1ALDH1A1
SCHEMBL282140 0.73 MEN1 (0.35) MEN1MAPTKMT2A
SCHEMBL9513607 0.71 MEN1 (0.34) MEN1KMT2A
SCHEMBL8735002 0.69 CES2 (0.31)
SCHEMBL8735023 0.69 CES2 (0.31)
SCHEMBL10755280 0.69 NOTUM (0.31)
SCHEMBL3569028 0.69 MEN1 (0.37) MEN1KMT2A
SCHEMBL10744284 0.69 MEN1 (0.37) MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3633 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
US-20250176551-A1 METHOD FOR CONTROLLING THE GROWTH OF UNDESIRABLE VEGETATION UPL LTD (IN) 2025-06-05 US claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20250113826-A1 AN AGROCHEMICAL COMBINATION UPL LTD (IN) 2025-04-10 US claimed
US-20240172758-A1 METHOD FOR CONTROLLING THE GROWTH OF UNDESIRABLE VEGETATION UPL LIMITED (IN) 2024-05-30 US claimed
US-20230247988-A1 HERBICIDE COMBINATIONS UPL LTD (IN) 2023-08-10 US claimed
US-20230139897-A1 SOLID HERBICIDE COMPOSITION AND THE USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2023-05-04 US claimed
EP-4171230-A1 HERBICIDE COMBINATIONS UPL Limited (IN) 2023-05-03 EP claimed
US-20120110702-A1 Pesticidal Compositions and Processes Related Thereto CORTEVA AGRISCIENCE LLC 2012-05-03 US claimed
US-20120110701-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2012-05-03 US claimed
US-20110190133-A1 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC 2011-08-04 US claimed
WO-2010022251-A2 GABA/PESTICIDAL COMBINATIONS PLANT HEALTH CARE, INC. (US) 2010-02-25 WO claimed
US-20100048397-A1 GABA/Pesticidal Combinations PLANT HEALTH CARE, INC. 2010-02-25 US claimed
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds CORET JOEL M 2008-05-15 US claimed
WO-2006009937-A2 NOVEL ESTERS AS USEFUL BROAD SPECTRUM HERBICIDAL COMPOUNDS CORET JOEL MARCEL (US) 2006-01-26 WO claimed
US-20050282706-A1 Novel esters as useful broad spectrum herbicidal compounds CORET JOEL M 2005-12-22 US claimed
EP-0257845-B1 METHOD OF PRODUCING VARIEGATED PLANTS Taguchi, Masayasu (JP) 1991-10-16 EP claimed
EP-0257845-A2 Method of producing variegated plants Taguchi, Masayasu (JP) 1988-03-02 EP claimed