SCHEMBL8734994

SCHEMBL8734994

CCOP(=O)(COS(=O)(=O)c1c(F)cccc1CC)OC(C)C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8730144 0.93 KEAP1 (0.30)
SCHEMBL8732694 0.90 CA12 (0.35) CA12CA1CA2CA9
SCHEMBL8732456 0.89
SCHEMBL8732876 0.85 ALDH1A1 (0.31) CA12CA1CA2CA9
SCHEMBL8732856 0.85 LMNA (0.30) CA12CA1CA2CA9
SCHEMBL8730154 0.85 EPHX2 (0.31)
SCHEMBL8729942 0.85 CA12 (0.30) CA12CA1CA2CA9
SCHEMBL8732724 0.84 KAT6A (0.30) CA12CA1CA2CA9
SCHEMBL8732676 0.84 CA12 (0.31) CA12CA1CA2CA9
SCHEMBL8734910 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed