Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8735170

C[I+](C)(c1ccccc1)c1ccccc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.47

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.47
PTPN1 P18031 1/20 0.39
KCNH2 Q12809 9/20 0.37
ACHE P22303 5/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
HSD11B1 P28845 1/20 0.35
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL443422 0.82 GPR3 (0.46) GPR3PTPN1KCNH2ACHECA1
Sulfuric Acid SCHEMBL7742383 0.81 TSHR (0.41) CA1CA2CA9
Trifluoromethanesulfonic Acid SCHEMBL8640775 0.75 HSD11B1 (0.41) GPR3PTPN1CA1CA2HSD11B1
Trifluoromethanesulfonic Acid SCHEMBL19915287 0.75 GPR3 (0.50) GPR3PTPN1KCNH2ACHECA1
Trifluoromethanesulfonic Acid SCHEMBL29612831 0.75 GPR3 (0.50) GPR3PTPN1KCNH2ACHECA1
Trifluoromethanesulfonic Acid SCHEMBL28131824 0.75 GPR3 (0.50) GPR3PTPN1KCNH2ACHECA1
Trifluoromethanesulfonic Acid SCHEMBL28640172 0.75 GPR3 (0.50) GPR3PTPN1KCNH2ACHECA1
Trifluoromethanesulfonic Acid SCHEMBL523876 0.75 GPR3 (0.50) GPR3PTPN1KCNH2ACHECA1
Trifluoromethanesulfonic Acid SCHEMBL29576707 0.75 GPR3 (0.50) GPR3PTPN1KCNH2ACHECA1
Trifluoromethanesulfonic Acid SCHEMBL6923668 0.74 GPR3 (0.53) GPR3PTPN1KCNH2ACHECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP disclosed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US disclosed