Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8735181

Clc1ccc([I+]c2ccccc2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.42
KCNH2 Q12809 1/20 0.42
ALDH1A1 P00352 3/20 0.40
MMP2 P08253 1/20 0.40
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
PSEN1 P49768 3/20 0.35
PSEN2 P49810 3/20 0.35
APH1B Q8WW43 3/20 0.35
NCSTN Q92542 3/20 0.35
APH1A Q96BI3 3/20 0.35
PSENEN Q9NZ42 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
FLT1 P17948 1/20 0.35
FLT4 P35916 1/20 0.35
KDR P35968 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PTPN1 P18031 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL1805120 0.93 KCNH2 (0.42) GPR3KCNH2ALDH1A1MMP2CYP3A4
Trifluoromethanesulfonic Acid SCHEMBL36177 0.89 GPR3 (0.50) GPR3KCNH2ALDH1A1PTPN1CA1
Trifluoromethanesulfonic Acid SCHEMBL503264 0.84 GPR3 (0.43) GPR3ALDH1A1MAPK1PSEN1PSEN2
Trifluoromethanesulfonic Acid SCHEMBL8461538 0.84 KCNH2 (0.39) GPR3KCNH2ALDH1A1MMP2CYP3A4
Trifluoromethanesulfonic Acid SCHEMBL9279810 0.84 GPR3 (0.46) GPR3KCNH2ALDH1A1MAPK1L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL8735160 0.83 GPR3 (0.42) GPR3KCNH2MMP2PTPN1CA1
Trifluoromethanesulfonic Acid SCHEMBL2851342 0.83 GPR3 (0.47) GPR3KCNH2ALDH1A1MMP2CYP3A4
Trifluoromethanesulfonic Acid SCHEMBL3147966 0.83 GPR3 (0.42) GPR3KCNH2MMP2PTPN1CA12
Trifluoromethanesulfonic Acid SCHEMBL30407359 0.81 GPR3 (0.43) GPR3KCNH2PTPN1CA1CA2
Trifluoromethanesulfonic Acid SCHEMBL1270048 0.80 HSD11B1 (0.41) GPR3ALDH1A1PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP disclosed