SCHEMBL8735223

SCHEMBL8735223

C/C=C(/OCO)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 2/20 0.36
TSHR P16473 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 4/20 0.35
MAPK1 P28482 2/20 0.35
HIF1A Q16665 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A3 Q01959 1/20 0.35
AKT1 P31749 1/20 0.35
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
NCOR2 Q9Y618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734905 1.00 LMNA (0.38) LMNATDP1TSHRCYP1A2CYP2C9
SCHEMBL9492821 0.83 ALDH1A1 (0.42) LMNATDP1TSHRCYP1A2CYP2C9
SCHEMBL9712464 0.83 ALDH1A1 (0.42) LMNATDP1TSHRCYP1A2CYP2C9
SCHEMBL6669479 0.83 MEN1 (0.46) LMNATSHRKMT2AMAPK1ALDH1A1
SCHEMBL2777335 0.79 TSHR (0.50) LMNATDP1TSHRKMT2AMAPK1
SCHEMBL8588497 0.79 TSHR (0.50) LMNATDP1TSHRKMT2AMAPK1
SCHEMBL342989 0.79 TSHR (0.50) LMNATDP1TSHRKMT2AMAPK1
SCHEMBL2918927 0.72 TDP1 (0.51) TDP1TSHRKMT2AHIF1AALDH1A1
SCHEMBL2918930 0.72 TDP1 (0.51) TDP1TSHRKMT2AHIF1AALDH1A1
SCHEMBL10616145 0.71 MAPT (0.39) LMNATDP1TSHRKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566780-B1 Heat-resistant resin composition KONISHI CO LTD (JP) 1998-03-11 EP claimed