Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492821 | 1.00 | ALDH1A1 (0.42) | ALDH1A1RECQLGAALMNATDP1 | |
| SCHEMBL8735223 | 0.83 | LMNA (0.38) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL8734905 | 0.83 | LMNA (0.38) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL6669479 | 0.79 | MEN1 (0.46) | ALDH1A1GAALMNATSHRMAPK1 | |
| SCHEMBL342989 | 0.76 | TSHR (0.50) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL2777335 | 0.76 | TSHR (0.50) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL8588497 | 0.76 | TSHR (0.50) | ALDH1A1GAALMNATDP1TSHR | |
| SCHEMBL17844755 | 0.75 | ALDH1A1 (0.45) | ALDH1A1RECQLGAALMNATDP1 | |
| Propene SCHEMBL43766 | 0.74 | LMNA (0.61) | ALDH1A1GAALMNATDP1SLC7A5 | |
| SCHEMBL25178945 | 0.72 | GPR52 (0.47) | ALDH1A1LMNATDP1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |