SCHEMBL4890609

SCHEMBL4890609

O=C(O)c1ccc(Oc2ccc(C(F)(F)C(F)(F)C(F)F)cc2)cc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.51
ALDH1A1 P00352 3/20 0.46
HPSE Q9Y251 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.42
APEX1 P27695 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
TDP1 Q9NUW8 5/20 0.41
LMNA P02545 1/20 0.41
GALK1 P51570 1/20 0.41
CASP6 P55212 1/20 0.41
MCL1 Q07820 1/20 0.41
PLEC Q15149 1/20 0.41
DUSP3 P51452 1/20 0.40
PTPN5 P54829 1/20 0.40
PTPN11 Q06124 1/20 0.40
PYGL P06737 4/20 0.40
PYGM P11217 2/20 0.40
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9128762 0.87 POLB (0.55) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL9129781 0.85 POLB (0.54) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL10625500 0.85 POLB (0.54) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL9131653 0.85 POLB (0.54) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL28412795 0.84 ALDH1A1 (0.49) POLBALDH1A1L3MBTL1APEX1CTDSP1
SCHEMBL523943 0.83 POLB (0.58) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL873525 0.83 HSD17B10 (0.46) ALDH1A1TDP1KDM4EHPGDHSD17B10
SCHEMBL9460665 0.83 POLB (0.51) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL4890621 0.83 POLB (0.51) POLBALDH1A1HPSEL3MBTL1APEX1
SCHEMBL125376 0.81 POLB (0.55) POLBALDH1A1HPSEL3MBTL1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113462278-B Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2024-06-07 CN disclosed
CN-113462277-B Varnish composition and method for producing polyimide resin 东京应化工业株式会社 2024-04-19 CN disclosed
CN-113354945-B Varnish composition and method for producing polyimide resin 东京应化工业株式会社 2024-03-12 CN disclosed
CN-110776738-B Composition, cured product, method for producing cured product, salt, and use thereof 东京应化工业株式会社 2023-11-24 CN disclosed
CN-116353168-A Resin laminate, circuit board, electronic component, and electronic device 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-116367413-A Metal-clad laminate and circuit board 日铁化学材料株式会社 2023-06-30 CN disclosed
CN-116333585-A Varnish composition, method for producing varnish composition, and method for producing polyimide resin 东京应化工业株式会社 2023-06-27 CN disclosed
CN-116254048-A Varnish composition, method for producing varnish composition, and method for producing polyimide resin 东京应化工业株式会社 2023-06-13 CN disclosed
CN-114806395-A Polyimide precursor varnish and method for producing same, polyimide and method for producing same, flexible device, and laminate for wiring board 日铁化学材料株式会社 2022-07-29 CN disclosed
CN-114644859-A Coloring composition, colored film, and method for forming colored film 东京应化工业株式会社 2022-06-21 CN disclosed
CN-113462278-A Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2021-10-01 CN disclosed
CN-113462277-A Varnish composition and method for producing polyimide resin 东京应化工业株式会社 2021-10-01 CN disclosed
CN-113354945-A Varnish composition and method for producing polyimide resin 东京应化工业株式会社 2021-09-07 CN disclosed
CN-112752787-A Polyimide precursor, polyimide obtained therefrom, and flexible device 日铁化学材料株式会社 2021-05-04 CN disclosed
CN-107429059-B Energy-sensitive resin composition 东京应化工业株式会社 2020-10-23 CN disclosed
CN-111378280-A Polyimide precursor composition, polyimide film produced from same, flexible device, and method for producing polyimide film 日铁化学材料株式会社 2020-07-07 CN disclosed
CN-110776738-A Composition, cured product, method for producing cured product, salt, and use thereof 东京应化工业株式会社 2020-02-11 CN disclosed
US-7450803-B2 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20070086705-A1 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-04-19 US disclosed
US-5598501-A Polyimide optical waveguide and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1997-01-28 US disclosed