Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264165 | 0.83 | LMNA (0.44) | LMNAMAPTDUTCYP2D6CHRM2 | |
| SCHEMBL20600150 | 0.80 | LMNA (0.49) | LMNADUTCYP2D6CHRM2CHRM1 | |
| SCHEMBL20599883 | 0.80 | LMNA (0.49) | LMNADUTCYP2D6CHRM2CHRM1 | |
| SCHEMBL8477474 | 0.79 | LMNA (0.51) | LMNADUTCHRM3HRH1ATM | |
| SCHEMBL8477470 | 0.79 | LMNA (0.51) | LMNADUTCHRM3HRH1ATM | |
| SCHEMBL8481946 | 0.79 | LMNA (0.51) | LMNADUTCHRM3HRH1ATM | |
| SCHEMBL10123845 | 0.77 | LMNA (0.51) | LMNAMAPTCYP2D6CHRM2CHRM1 | |
| SCHEMBL9839245 | 0.76 | LMNA (0.66) | LMNAMAPTNPSR1CYP2D6CHRM2 | |
| SCHEMBL8343216 | 0.76 | LMNA (0.53) | LMNADUTCHRM2CHRM1CHRM3 | |
| SCHEMBL8342637 | 0.76 | LMNA (0.53) | LMNADUTCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5738872-A | ANTIALLERGENS, ANTIHISTAMINES; BIOAVAILABILITY | HOECHST MARION ROUSSEL, INC. (US) | 1998-04-14 | — | — | US | disclosed |