SCHEMBL269381

SCHEMBL269381

Cc1ccccc1C(=O)CC(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 2/20 0.68
FEN1 P39748 2/20 0.68
KMT2A Q03164 8/20 0.65
MEN1 O00255 7/20 0.65
HPGD P15428 7/20 0.65
SMN1; SMN2 Q16637 5/20 0.65
MAPT P10636 4/20 0.65
CYP3A4 P08684 3/20 0.65
KDM4E B2RXH2 2/20 0.65
ALOX15 P16050 2/20 0.65
MAPK1 P28482 2/20 0.65
CES1 P23141 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
NPC1 O15118 8/20 0.63
RAB9A P51151 6/20 0.63
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
ALDH1A1 P00352 2/20 0.53
PLOD2 O00469 1/20 0.53
PLOD3 O60568 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29483365 1.00 ERCC5 (0.68) ERCC5FEN1KMT2AMEN1HPGD
SCHEMBL28972917 0.93 ERCC5 (0.60) ERCC5FEN1KMT2AMEN1HPGD
SCHEMBL28972918 0.93 ERCC5 (0.60) ERCC5FEN1KMT2AMEN1HPGD
SCHEMBL8735550 0.90 ERCC5 (0.74) ERCC5FEN1KMT2AMEN1HPGD
SCHEMBL11289405 0.86 KMT2A (0.81) ERCC5FEN1KMT2AMEN1HPGD
SCHEMBL15979719 0.85 NR4A2 (0.59) ERCC5FEN1KMT2AHPGDMAPT
SCHEMBL3660192 0.84 ERCC5 (0.72) ERCC5FEN1KMT2AMEN1HPGD
SCHEMBL270726 0.82 KMT2A (0.71) KMT2AMEN1HPGDSMN1; SMN2MAPT
SCHEMBL269145 0.82 MEN1 (0.66) KMT2AMEN1HPGDSMN1; SMN2MAPT
Dibenzoylmethane SCHEMBL39582 0.81 MEN1 (1.00) ERCC5FEN1KMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395733-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2024-07-10 EP claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 US claimed
CN-117897133-A Photoprotective personal care compositions 联合利华知识产权控股有限公司 2024-04-16 CN claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 CN claimed
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 WO claimed
WO-2023030963-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-03-09 WO claimed
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 CN claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 US claimed
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 CN claimed
EP-0780119-A1 Light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-06-25 EP claimed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 EP claimed
US-5587150-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-12-24 US claimed
EP-0748624-A1 Composition containing a dibenzoylmethane derivative and a nanopigment of titanium dioxide and uses thereof L'OREAL (FR) 1996-12-18 EP claimed
US-5576354-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-11-19 US claimed
EP-0717982-A1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use L'OREAL (FR) 1996-06-26 EP claimed
EP-0709080-A1 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1996-05-01 EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 EP claimed
EP-0514491-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE. OREAL (FR) 1992-11-25 EP claimed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 WO claimed