SCHEMBL8735560

SCHEMBL8735560

SC1=NSc2ccccc2C1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 3/20 0.30
KMT2A Q03164 3/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
ATM Q13315 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3081411 0.78 ALDH1A1 (0.38) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL3129155 0.75 MEN1 (0.37) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL1868060 0.75 ALDH1A1 (0.36) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL11708484 0.75 HPGD (0.37) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL4103011 0.75 ALDH1A1 (0.37) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL27528131 0.71 KDM4E (0.33) ALDH1A1HPGDKDM4E
SCHEMBL27272787 0.71 ALDH1A1 (0.37) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL9211141 0.69 ALDH1A1 (0.47) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL8288 0.69 MAOA (0.38) ALDH1A1HPGDKDM4EMEN1KMT2A
SCHEMBL3619022 0.68 ALDH1A1 (0.36) ALDH1A1HPGDKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428153-A2 Thermoplastic elastomer of propylene Polymer Material and Crosslinked Ethylene-Propylene Rubber MONTELL NORTH AMERICA INC. (US) 1991-05-22 EP claimed
EP-0738286-B1 ACTIVATOR FORMULATION AND COMPOSITION UTILIZING SAME DYMAX CORP (US) 1998-08-12 EP disclosed
US-5512608-A BLEND OF ACRYLATE COMPOUND AND ACTIVATOR DYMAX CORPORATION (US) 1996-04-30 US disclosed
US-5385958-A Curable mixture of acrylates, vinyl ether reactive diluent, epoxy compounds and active oxygen component; adhesives, sealants, coatings DYMAX CORPORATION (US) 1995-01-31 US disclosed
US-4276373-A SILVER HALIDE EMULSION, MONOAZO DYE AGFA-GEVAERT, A.G. (DE) 1981-06-30 US disclosed
US-3940532-A ARTIFICIAL LEATHER THE FIBERWOVEN CORPORATION (US) 1976-02-24 US disclosed
US-3936555-A Filled textile fabric with a density gradient THE FIBERWOVEN CORPORATION (US) 1976-02-03 US disclosed
US-3935350-A Suppression of crevice corrosion in gasketed titanium crevices by the use of rubber compound gaskets substantially free of calcium PPG INDUSTRIES, INC. (US) 1976-01-27 US disclosed