SCHEMBL8735582

SCHEMBL8735582

CCOP(=O)(COS(=O)(=O)c1c(F)cccc1SC)OCC

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732876 0.91 ALDH1A1 (0.31) CA12CA1CA2CA9
SCHEMBL8734629 0.89 KAT6A (0.33) KAT6ACA12CA1CA2CA9
SCHEMBL8735685 0.87 TSHR (0.30) NPSR1
SCHEMBL8732260 0.86 LMNA (0.32) LMNANPSR1KCNH2
SCHEMBL8735683 0.86 ALDH1A1 (0.34) LMNANPSR1KCNH2
SCHEMBL8732002 0.84 STK10 (0.31)
SCHEMBL8732234 0.84 NPC1 (0.30)
SCHEMBL8734989 0.83 KDM4E (0.32) KAT6ALMNA
SCHEMBL8732694 0.83 CA12 (0.35) KAT6ACA12CA1CA2CA9
SCHEMBL8735727 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed