SCHEMBL8734989

SCHEMBL8734989

CSc1cccc(F)c1S(=O)(=O)OCP(=O)(O)O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
PPIA P62937 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
KAT6A Q92794 1/20 0.31
PKM P14618 1/20 0.30
PKLR P30613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731835 0.87 KAT6A (0.34) HPGDHSD17B10KAT6A
SCHEMBL8732619 0.85 MAPT (0.36) KMT2ALMNA
SCHEMBL8734986 0.84 FFAR4 (0.31)
SCHEMBL8734484 0.84 LMNA (0.32) LMNA
SCHEMBL8735582 0.83 KAT6A (0.31) LMNAKAT6A
SCHEMBL8729834 0.83 STK10 (0.33)
SCHEMBL8732234 0.82 NPC1 (0.30)
SCHEMBL8735644 0.81
SCHEMBL8734733 0.81 KEAP1 (0.35) HPGDKMT2AHSD17B10LMNAKAT6A
SCHEMBL8735587 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed