⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040988 | 0.97 | — | — | |
| SCHEMBL28050407 | 0.97 | — | — | |
| SCHEMBL15910004 | 0.88 | CES2 (0.39) | — | |
| SCHEMBL873570 | 0.87 | CES2 (0.67) | — | |
| SCHEMBL873874 | 0.87 | — | — | |
| SCHEMBL18759144 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL25248339 | 0.84 | CES2 (0.63) | — | |
| SCHEMBL2650157 | 0.84 | CES2 (0.72) | — | |
| SCHEMBL6159646 | 0.84 | CES2 (0.72) | — | |
| SCHEMBL18199938 | 0.84 | CES2 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120005847-A | Alpha-hydroxy-beta-keto acid synthase for catalyzing alpha-keto acid coupling reaction | 北京大学 | 2025-05-16 | — | — | CN | claimed |
| EP-2643000-A2 | THERAPEUTIC PIPERAZINES | Dart Neuroscience (Cayman) Ltd (KY) | 2013-10-02 | — | — | EP | claimed |
| WO-2012040258-A2 | THERAPEUTIC PIPERAZINES | HELICON THERAPEUTICS, INC. (US) | 2012-03-29 | — | — | WO | claimed |
| US-20110065691-A1 | THERAPEUTIC PIPERAZINES | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2011-03-17 | — | — | US | claimed |
| EP-4729513-A1 | A-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | Nanjing Chempion Biotechnology Co., Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| US-20260055113-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | HOFFMANN-LA ROCHE INC. (US) | 2026-02-26 | — | — | US | disclosed |
| US-12522584-B2 | 3,4-dihydroisoquinoline compound and use thereof | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD (CN) | 2026-01-13 | — | — | US | disclosed |
| US-20250353817-A1 | INTERLUKIN-17A INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4568965-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| US-20250188040-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS INC | 2025-06-12 | — | — | US | disclosed |
| EP-4559912-A1 | SULFUR-CONTAINING HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2025-05-28 | — | — | EP | disclosed |
| CN-120005847-A | Alpha-hydroxy-beta-keto acid synthase for catalyzing alpha-keto acid coupling reaction | 北京大学 | 2025-05-16 | — | — | CN | disclosed |
| EP-0108708-B1 | N-(CYCLOPROPYL-TRIAZINYL- AND -PYRIMIDINYL)-N'-(ARYLSULFONYL) UREAS WITH HERBICIDAL ACTIVITY | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |
| US-4600428-A | N-(cyclopropyl-pyrimidinyl-N'-(aryl-sulfonyl) ureas having herbicidal activity | CIBA-GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| EP-0148004-A2 | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1985-07-10 | — | — | EP | disclosed |
| WO-1985002181-A1 | PREPARATION OF CYCLIC-KETO-ACIDS | ETHYL CORPORATION (US) | 1985-05-23 | — | — | WO | disclosed |
| EP-0141876-A1 | Preparation of cyclic-keto-acids | ETHYL CORPORATION (US) | 1985-05-22 | — | — | EP | disclosed |
| US-4515626-A | PLANT GROWTH REGULATORS | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4473706-A | Preparation of cyclic-keto-acids | ETHYL CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| EP-0108708-A2 | N-(cyclopropyl-triazinyl- and -pyrimidinyl)-N'-(arylsulfonyl) ureas with herbicidal activity | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |