SCHEMBL8735701

SCHEMBL8735701

CC(C)OP(C)(=O)COS(=O)(=O)c1ccc(F)cc1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
CNR2 P34972 3/20 0.31
CNR1 P21554 2/20 0.31
HSD11B1 P28845 4/20 0.31
EPHX2 P34913 1/20 0.30
NR3C2 P08235 1/20 0.30
TRPM8 Q7Z2W7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732795 0.89 IDO1 (0.33) IDO1DPP4DPP8DPP9DPP7
SCHEMBL8734997 0.86 CNR2 (0.32) IDO1DPP4DPP8DPP9DPP7
SCHEMBL8732229 0.84 MEN1 (0.38) DPP4DPP8DPP9DPP7HSD11B1
SCHEMBL8735757 0.84
SCHEMBL8732898 0.83 PSEN1 (0.33)
SCHEMBL8731772 0.80 IDO1 (0.37) IDO1CNR2CNR1HSD11B1EPHX2
SCHEMBL8729956 0.78 HSD11B1 (0.35) IDO1CNR2CNR1HSD11B1EPHX2
SCHEMBL8735606 0.77 ALDH1A1 (0.31) HSD11B1
SCHEMBL8732451 0.76 TRPM8 (0.32) TRPM8
SCHEMBL8729941 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed