Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735192 | 0.76 | POLB (0.36) | NPC1RAB9APOLBKDM4EALDH1A1 | |
| SCHEMBL8734969 | 0.76 | PTGS2 (0.41) | NPC1RAB9ACYP1A2CYP2C9POLB | |
| SCHEMBL8735823 | 0.75 | PTGS2 (0.41) | NPC1RAB9ACYP1A2CYP2C9POLB | |
| SCHEMBL9017593 | 0.75 | POLB (0.47) | NPC1RAB9ACYP1A2CYP2C9POLB | |
| SCHEMBL8735214 | 0.73 | CYP1A2 (0.39) | NPC1RAB9ACYP1A2CYP2C9POLB | |
| SCHEMBL8735191 | 0.73 | PTGS2 (0.41) | NPC1RAB9ACYP1A2CYP2C9POLB | |
| SCHEMBL7218206 | 0.70 | L3MBTL1 (0.36) | NPC1RAB9AL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL7218228 | 0.69 | ALDH1A1 (0.42) | RAB9APOLBALDH1A1 | |
| SCHEMBL8732688 | 0.69 | POLB (0.33) | POLBALDH1A1LMNA | |
| SCHEMBL10294121 | 0.68 | KDM4E (0.51) | NPC1RAB9AL3MBTL1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749416-B1 | SELECTED BENZAMIDE FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO CO (US) | 1998-12-23 | — | — | EP | disclosed |