Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 4/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735954 | 1.00 | LCK (0.38) | LCKRELANFE2L2APPABL1 | |
| SCHEMBL8734651 | 0.95 | NFE2L2 (0.43) | RELANFE2L2CYP19A1 | |
| SCHEMBL8734646 | 0.95 | NFE2L2 (0.43) | RELANFE2L2CYP19A1 | |
| SCHEMBL8736691 | 0.80 | NFE2L2 (0.43) | RELANFE2L2CYP19A1 | |
| SCHEMBL8736695 | 0.80 | NFE2L2 (0.43) | RELANFE2L2CYP19A1 | |
| SCHEMBL8734121 | 0.77 | NFE2L2 (0.44) | LCKRELANFE2L2APPABL1 | |
| SCHEMBL8734119 | 0.77 | NFE2L2 (0.44) | LCKRELANFE2L2APPABL1 | |
| SCHEMBL8736129 | 0.77 | TRPA1 (0.47) | RELANFE2L2CYP19A1 | |
| SCHEMBL8736130 | 0.77 | TRPA1 (0.47) | RELANFE2L2CYP19A1 | |
| SCHEMBL8736156 | 0.75 | SMN1; SMN2 (0.36) | RELANFE2L2APPABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |