Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734121 | 1.00 | NFE2L2 (0.44) | NFE2L2CYP19A1MAOAMAOBACHE | |
| SCHEMBL8733085 | 0.94 | NFE2L2 (0.50) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL8733083 | 0.94 | NFE2L2 (0.50) | NFE2L2CYP19A1MAOAMAOBRELA | |
| SCHEMBL8733093 | 0.92 | NFE2L2 (0.43) | NFE2L2CYP19A1MAOAMAOBACHE | |
| SCHEMBL8733095 | 0.92 | NFE2L2 (0.43) | NFE2L2CYP19A1MAOAMAOBACHE | |
| SCHEMBL13636781 | 0.85 | APP (0.46) | NFE2L2CYP19A1RELANPC1MAPT | |
| SCHEMBL3157051 | 0.82 | TP53 (0.54) | ACHEMAPTPTGS2 | |
| SCHEMBL310345 | 0.82 | ALDH1A1 (0.48) | MAOAMAOBACHENPC1PTGS2 | |
| SCHEMBL9116838 | 0.82 | ACHE (0.42) | ACHE | |
| SCHEMBL8347751 | 0.81 | TTR (0.54) | ACHENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |