Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHAT | P28329 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736170 | 1.00 | TRPA1 (0.47) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL8736149 | 0.92 | SMN1; SMN2 (0.36) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL8736147 | 0.92 | SMN1; SMN2 (0.36) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL8736129 | 0.85 | TRPA1 (0.47) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL8736130 | 0.85 | TRPA1 (0.47) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL8736691 | 0.84 | NFE2L2 (0.43) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL8736695 | 0.84 | NFE2L2 (0.43) | TRPA1RELANFE2L2CYP19A1MAOA | |
| SCHEMBL339880 | 0.81 | ESR1 (0.39) | — | |
| SCHEMBL6547160 | 0.79 | ESR1 (0.38) | RELAHPGD | |
| SCHEMBL6547559 | 0.79 | ESR1 (0.38) | RELAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722959-B1 | Highly oxygen-permeable heat-resistant material | MENICON CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5587445-A | Highly oxygen-permeable heat-resistant material | MENICON CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0722959-A2 | Highly oxygen-permeable heat-resistant material | Menicon Co., Ltd. (JP) | 1996-07-24 | — | — | EP | disclosed |