Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111544 | 0.89 | KMT2A (0.55) | RAB9ANPC1KMT2AL3MBTL1KDM4E | |
| SCHEMBL697332 | 0.89 | NPC1 (0.54) | RAB9ANPC1KMT2AHDAC1F2RL1 | |
| SCHEMBL7519925 | 0.89 | RAB9A (0.54) | RAB9ANPC1KMT2AATMTDP1 | |
| SCHEMBL4069827 | 0.89 | NPC1 (0.54) | RAB9ANPC1KMT2ATDP1L3MBTL1 | |
| SCHEMBL13947485 | 0.89 | RAB9A (0.54) | RAB9ANPC1KMT2AATMTDP1 | |
| SCHEMBL653441 | 0.87 | RAB9A (0.69) | RAB9ANPC1KMT2AATMTDP1 | |
| SCHEMBL112360 | 0.85 | NPC1 (0.50) | RAB9ANPC1KMT2APRKCI | |
| SCHEMBL10757464 | 0.83 | CES2 (0.54) | RAB9ANPC1KMT2AHTTKDM4E | |
| SCHEMBL173730 | 0.82 | CD74 (0.63) | RAB9ANPC1KMT2A | |
| SCHEMBL6680848 | 0.82 | NPC1 (0.58) | RAB9ANPC1KMT2ATDP1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60127325-A | — | — | None | — | — | JP | disclosed |
| EP-0661309-B1 | Use of hydroperoxide derivatives of Cyclo-olefin copolymers | TICONA GMBH (DE) | 1998-11-25 | — | — | EP | disclosed |
| EP-0661309-A2 | Cyclo-olefin copolymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |
| JP-S60127325-A | MANUFACTURE OF NYLON BLOCK COPOLYMER | SUMITOMO CHEM CO LTD | 1985-07-08 | — | — | JP | disclosed |
| US-4388189-A | AMINE-CONTAINING POLYMER, CROSSLINKING | TEIJIN LIMITED (JP) | 1983-06-14 | — | — | US | disclosed |
| EP-0031730-A2 | The improved semipermeable composite membranes and process for their production | TEIJIN LIMITED (JP) | 1981-07-08 | — | — | EP | disclosed |